STAT3 and autoimmune thyroid disease: In the autoimmune thyroiditis mice, the expressions of retinoic acid-related orphan receptor gamma t (RORγt), retinoic acid-related orphan receptor alpha (RORα), and signal transducer and activator of transcription 3 (STAT3) were much higher, but the expression of forkhead/winged helix transcription factor p3 (Foxp3) is significantly lower [180].