Conversely, the low association of GLP1 analogues with biguanides was unexpected; a possible explanation would be that SGLT2 inhibitors were preferred to GLP1 analogues, as both combinations (metformin + GLP1 analogues or metformin + SGLT2 inhibitors) are recommended by the Swiss Society for Endocrinology and Diabetes [6]. This evidence concerns the gene GCG and diabetes mellitus.