Further investigation using the UALCAN database to scrutinize NQO1 mRNA expression in conjunction with clinicopathological variables across 41 colorectal and 286 CRC specimens demonstrated that increased NQO1 expression significantly correlated with age, clinical stage, and lymph node involvement in patients with CRC (Fig. 1D, P < 0.01). The gene discussed is NQO1; the disease is colorectal carcinoma.