DDR2 and familial pancreatic carcinoma: The BRCA and male PAAD ColX modules additionally contain DDR2, a COL10A1 receptor which has been shown to sustain the EMT phenotype to promote metastasis in breast cancer as well as induce EMT to accelerate the progression of pancreatic cancer [72, 73], consistent with fibrosis and metastasis-associated EMT pathway genes being most strongly enriched in those two ColX modules.