Various other CAF-specific genes are co-modularized with COL10A1, including inflammatory CAF markers CXCL12 (BRCA) and CXCL14 (female PAAD), vascular CAF markers ACTA2 (all ColX modules) and NOTCH3 (PAAD and male PAAD), and tumor-like CAF markers PDPN (BRCA, PAAD, and male PAAD) and TMEM158 (male PAAD). The gene discussed is NOTCH3; the disease is pancreatic adenocarcinoma.