TGFB1 and familial pancreatic carcinoma: Corroborating the GO enrichment of EMT and related pro-metastatic pathways, FOXH1 is an inducer of the TGF-β/Nodal/Activin signaling pathway and has been implicated in proliferation, migration, and invasion of both breast and pancreatic cancer [74, 75] (Table S5A).