SPP1 is a phosphorylated acidic glycoprotein adhesion molecule that is frequently upregulated during event‐induced inflammation, including infection [31, 32, 33], trauma [34, 35], allergy [36, 37, 38], and autoimmunity [39, 40, 41], performing biological functions through autocrine and/or paracrine signaling. The gene discussed is SPP1; the disease is Autoimmunity.