The results revealed that after irradiation, tumor cells exhibited obvious morphological changes (Fig. 7a), and the expression levels of the stress-inducible proteins ULBP1, ULBP2, HSP60 and MICA/B were also significantly increased in irradiated tumor cells (Fig. 7b, Supplementary Data Fig. 17); these effects were accompanied by the significantly increased cytotoxicity of human γδ T cells against these irradiated cells in vitro (Fig. 7c, Supplementary Data Fig. 18). Here, TP53INP1 is linked to neoplasm.