Consistently, independent ELISA analysis of the SARS-CoV-2-positive samples showed high anti-spike S1 levels for all samples except the two behaving similarly to pre-COVID-19 samples (Fig. 3d), suggesting these two patient samples may have low levels of SARS-CoV-2 antibodies despite being from individuals with prior SARS-CoV-2-positive polymerase chain reaction (PCR) tests. The gene discussed is PSMD1; the disease is COVID-19.