CD4 and infection: Tem cells (CD44+ CD62L−, gated on CD4+ FOXP3+) were increased by MNV infection in Ncf190H mice, whereas naive Tregs (CD44− CD62L+, gated on CD4+ FOXP3+) and Tcm/ Tvm cells (CD62L+ CD44+, gated on CD4+ FOXP3+) were decreased (Fig. 6g).