All the altered molecules were noted in SCZ cases except for 27 molecules where the differential expression was noted in the early psychosis patients, which include majority of proteins and a miRNA: miR-137, COX 6A2, LETM1, TRPM4, NCLX, CACNA- 1 C, ATP synthase activity, mitofusin 2 (MFN2), cyclophilin D (CYPD), syntaphilin (SNPH), humanin, MOTS-c, Complex I, Complex III decreased, GFAP, C3b opsonin, C5b-9, CD55, LIF, hippocalcin, Kalirin, Neurogranin, beta-adducin, ankyrin-2, Apolipoprotein A4 (APOA4), P0C671 Chromosome 6 open reading frame 222 (C6orf222) and Sorcin. This evidence concerns the gene MT-RNR2 and psychotic disorder.