Besides, KDM6A is involved in the plasticity of small-cell lung cancer SCLC-A and SCLC-N subtypes (Duplaquet et al., 2023), and regulates cancer progression and metastasis via the TGF-β and Wnt pathways (Leng et al., 2020, Terashima et al., 2017). Here, TGFB1 is linked to small cell lung carcinoma.