TNF and autoimmune disease: Cerium oxide nanoparticles, known for their reactive oxygen species (ROS) scavenging activity, have shown effectiveness in the experimental autoimmune encephalomyelitis mouse model.[2] Additionally, graphene oxide nanosheets are effective in modulating neuroinflammation, chiefly by diminishing Ca2+ signaling in astrocytes, thereby contributing to multiple sclerosis therapy.[3] Furthermore, lipid nanoparticles have been employed to deliver nucleic acids, such as tumor necrosis factor (TNF)‐α siRNA, offering a novel treatment approach for autoimmune diseases, including rheumatoid arthritis.[4]