SNAI1 and colorectal carcinoma: To confirm the effects of ST6GAL1-induced sialylation on CRC cells, we treated SW48-OE and Caco2-EV cells with sialidase (NA), which significantly decreased sialylation in both cell lines, as evidenced by reduced SNA lectin and IFC staining (Figure 6A and 6B, and Figure S6A).