The lncRNA SNHG29, which acts as a tumor suppressor in acute myeloid leukemia (AML), interacts with E1A binding protein p300 (EP300), a histone acetyltransferase, and decreases the enrichment of EP300 at the promoters of AML-related genes, thus suppressing the expression of these genes by modulating EP300-mediated histone acetylation modification [70]. Here, EP300 is linked to neoplasm.