In hepatocellular carcinoma (HCC), LINC01089, a super enhancer-driven lncRNA, interacts with heterogeneous nuclear ribonucleoprotein M (hnRNPM) and promotes hnRNPM-mediated skipping of DIAPH3 exon 3, which contains an important m6A-modification site recognized by the m6A reader IGF2BP3 to stabilize DIAPH3 mRNA. Here, DIAPH3 is linked to hepatocellular carcinoma.