The phenotypic rescues in NMDAR‐SCZ and in the Shank3‐ASD mice models reports suggestively converge with published data that propose that multiple cognitive dysfunctions and symptoms presented by patients with BPD, such as dissociation, psychosis, and impaired nociception, may result from the dysregulation of the NMDA neurotransmission.45 Here, SHANK3 is linked to psychotic disorder.