STAT3 and neoplasm: In the subcutaneous xenograft model, STAT3 over‐expression increased tumour sizes and weights as well as MMP1/3 expressions, but these effects were reversed by ZFP14 over‐expression; besides, the change of phosphorylated STAT3 level in the tumours was basically accordant to that of the total STAT3 expression (Figure 8A–C).