In summary, with the assistance of IGF2BP2 as the reader, METTL14‐mediated m6A was shown to over‐express ZFP14, which could destabilise STAT3 protein via the ubiquitin–proteasome pathway, inhibiting the progression of ccRCC (Figure 9). The gene discussed is IGF2BP2; the disease is nonpapillary renal cell carcinoma.