EGFR and neuroblastoma: EGF binds to the epidermal growth factor receptor (EGFR), inducing auto‐phosphorylation to create binding sites for signalling molecules that stimulate proliferation.[89] Gangliosides are known inhibitors of this auto‐phosphorylation process and are therefore of interest in oncology research.[90, 91] In a study of a small ganglioside class, GT1b was found to be the most potent inhibitor of EGFR phosphorylation in the human neuroblastoma cell line, NBL‐W.[92] The authors postulated that the number and arrangement of Neu5Ac residues were a key contributor to the inhibitory potency.