Although the Medians of CD68+ and CD163+ cells in the TC group were almost similar, the balance of M1 and M2 macrophages varied significantly inside the group, so the CD68/CD163 ratio was low in patients with papillary thyroid carcinoma, comprising 0.563 (0.082–3.0). The gene discussed is CD68; the disease is thyroid gland papillary carcinoma.