The results of the study showed that while TNFSF10 expression was significantly higher in patients with T2DM and MAFLD, the expression levels of TNFRSF1A and SERPINB2 in the blood of patients with MAFLD and T2DM combined with MAFLD were significantly lower compared to healthy individuals (P<0.05) (Figure 8A). This evidence concerns the gene TNFSF10 and type 2 diabetes mellitus.