ERβ immunoexpression showed no significant differences between adenomyosis lesions and matched eutopic endometrium in all studies included in this review, whether the menstrual cycle phase and endometrial subregion were considered (Mehasseb et al., 2011) or not (Li et al., 2021; Samartzis et al., 2023). This evidence concerns the gene ESR2 and adenomyosis.