Through the preoperative evaluation of anesthesiology, the patient was transferred to the Department of Breast Surgery for modified radical mastectomy, and the pathological results showed invasive breast carcinoma (non‐special type, medium‐low differentiation, size 3 × 1.5 × 1 cm), multiple intravascular tumor emboli, lymph node metastatic carcinoma (right axillary 7/12) and immunohistochemical results: Estrogen receptor (ER/−), progesterone receptor (PR/−), human epidermal growth factor receptor 2 (Her2/−), Ki‐67 (80%). Here, ESR1 is linked to neoplasm.