TNFSF10 and neoplasm: Bagó et al first demonstrated that iNSCs possess tumor tropism similar to brain-derived NSCs and engineered mouse iNSCs to express a secreted variant of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL; iNSC-sTR), finding that iNSC-sTR therapy has significant therapeutic effects on malignant GBM.