Valproic acid in combination with the Ras inhibitor farnesylthiosalicylic acid (FTS) showed synergistic antiproliferative activity against BRAF-mutant ARO thyroid cancer cells, which was accompanied by suppression of Ras, survivin, and aurora A, leading to a mitotic crisis [Table 3][103]. The gene discussed is BIRC5; the disease is thyroid gland carcinoma.