In a pediatric AML case study by microarrays including a case with trisomy 6, Koh et al. [19], proposed than a poor prognosis related to this aneuploidy in AML could be due to candidate IRF4 (6p25.3) and DEK (6q22.3) genes associated to leukemogenesis. This evidence concerns the gene IRF4 and acute myeloid leukemia.