The results showed a positive correlation between the expression of S100A10 protein and extrathyroidal extension (p = 0.005) (Fig. 2A), lymph node metastasis (p = 0.013) (Fig. 2B), and upgraded ATA recurrence risk (p = 0.023) (Fig. 2C). This evidence concerns the gene S100A10 and metastatic malignant neoplasm in the lymph nodes.