Her both parents and her son did not develop GS-related symptoms, while the elder brother suffered from mild hypokalemia (3.26 ~ 3.45 mmol/L) and fatigue that were relieved after receiving oral potassium chloride sustained release tablets, which may support the previous findings of intermediate phenotypes in SLC12A3 pathogenic heterozygotes. Here, SLC12A3 is linked to Hypokalemia.