GHRH and acute myeloid leukemia: Consequently, the tumor inhibitory effects of GHRH antagonists in 16 types of human cancers, represented by nearly 50 human cancer lines including prostatic, breast, ovarian, renal, gastric, pancreatic, lung, and recently, acute myeloid leukemia appear to be based in part on the interference with the local stimulatory GHRH system.