In the GGTA1-knockout mouse model, animals were treated with PBS, Ad35(Luc), Adf35(O), Adf35(OG), Adf35(ON) and Adf35(OGN) respectively (n = 2 in each group), after immunization to generate anti-α-gal antibodies and tumor implantation (Fig. 1). This evidence concerns the gene GGTA1 and neoplasm.