However, due to medical (previous major abdominal surgery for rectal cancer), physical (obesity), and social factors (young and recently married), the patient was considered ineligible for/refused other treatments, thus receiving a single cycle of 5.8 GBq of [177Lu]Lu-PSMA-I&T followed by a BCR-Free Survival of 24 months [31]. The gene discussed is BCR; the disease is obesity due to melanocortin 4 receptor deficiency.