EPHA2 and neoplasm: Immunohistochemical staining revealed high EphA2 expression in the HT-1080 xenografts.<h4>Conclusion</h4>[<sup>89</sup>Zr]Zr-/[<sup>177</sup>Lu]Lu-EphA2 mAb demonstrated high retention in tumors, and [<sup>177</sup>Lu]Lu-EphA2 mAb exhibited marked tumor shrinkage.