On the other hand, an analysis of published cohorts of NSCLC patients and patients with stage I NSCLC revealed that low expression of TRIM8 was associated with shorter overall survival (n = 1411, P = 1.2E-13; Fig. 2D; n = 528, P = 1.5E–6; Fig. 2E). This evidence concerns the gene TRIM8 and non-small cell lung carcinoma.