RBFOX3 and Huntington disease: To investigate the epigenetic status of developmental genes in HD striatal cells, we generated ChIP-seq or CUT&Tag data on NeuN+ and NeuN- nuclei prepared from striatal tissue of 15 to 20 week old symptomatic HD R6/1 transgenic and control mice (Fig. 1a, b and Supplementary Fig. 1a–c).