Thus,they play an important role in the innate immune system,61,62 and TLR8 agonists have been studied for their potential role intreating cancer, asthma, viral and bacterial infections.62 We used OpenMMDL to simulateand analyze the structure of a TLR8 agonist C09 (PDB ID: 3W3J).63 This evidence concerns the gene TLR8 and cancer.