INS and type 1 diabetes mellitus: Importantly, there is potential for persons with type 1 diabetes using HCL systems to overtreat hypoglycemia despite presumed education and training at initiation of HCL systems to treat frank or impending hypoglycemia with only 5–10 g of carbohydrates due to the automated systems already attenuating or halting insulin delivery in anticipation of the low glucose [47].