MYLK and Aortic dissection: Inhibition of myosin light chain kinase by ML-7 or indirectly by a calcium channel blocker, nifedipine, or a Rho kinase inhibitor, fasudil, did not significantly alter the incidence of NE-triggered aortic dissection, although with a confounding lowering of blood pressure by the former 2 agents (Figure 7, G and H).