And conversely, PP2A subC level was decreased in the hippocampi of 3xTg-AD mice compared to WT mice, and the treatment with palm11-PrRP31 and liraglutide tended to increase its level, whereas the treatment with Dpr3-ghrelin significantly increased the level of PP2A subC (p = 0.011). This evidence concerns the gene PTPA and Alzheimer disease.