Analogously, recent studies have shown that TRIB3 dampens CD8+ T cell infiltration by repressing the STAT1‐CXCL10 axis and consequently induces immune evasion in colorectal cancer.[22] Thus, targeting TRIB3 can serve as a potential approach to remodel the constitution of tumor immune microenvironment and to sensitize tumors to various therapeutic strategies. Here, CD8A is linked to colorectal cancer.