CAV1 and chronic granulomatous disease: Caveolin‐1 (CAV1) is the primary constituent of CEM.[27] We previously found that CAV1 deficiency sensitizes mice to CGD.[3, 13] We detected no reductions in CAV1 mRNA levels in the gallbladder of miceWT and miceC70‐KO after they were fed the WD (Figure S13A, Supporting Information), whereas miceC70‐KO had significantly lower levels of CAV1 protein in the gallbladder in comparison to miceWT (Figure 5A).