has shown that RNase1 promotes CD4+ T‐cell activation to repress breast cancer growth through the activation of EphA4 on T cells.[34] In this previous study, ectopic overexpression of RNase1 in 4T1 cells inoculated into mice reduced tumor growth by an increased population of CD69‐positive CD4+ T cells. This evidence concerns the gene RNASE1 and breast carcinoma.