FLT3 and acute myeloid leukemia: Resembling the results in iMLL-AF9 mice,5 the number of BM CD45−Ter119−CD31− cells was significantly reduced, whereas nestin+ BMSCs were preserved, or even expanded, in FLT3-ITD;NPMc AML (Figures 1H–1L), suggesting that nestin+ BMSCs might also contribute to leukemogenesis in this AML subtype.