The first evidence that OvHV-2 is spread systemically not only by T-cells but also by monocytes was reported from experimental infections of sheep where some CD14+ monocytes were found to carry the virus.45 More recently, in our study on the arteritis in the rete mirabile of cattle with natural MCF, we found viral RNA in both circulating T-cells and monocytes.63 The results of the present study not only confirm this finding but also detected numerous infected T-cells and monocytes in lung capillaries and liver sinusoids, indicating their abundance in the circulating blood. The gene discussed is CD14; the disease is infection.