↑ impairs the LMO2 expression blocks the erythropoiesis process inhibits the erythroid differentiation increase the development of megakaryocytic cell increase platelet formation↓ stimulates the LMO2 expressioninduces the erythroid developmentinhibits the E-cadherin expression induces tumor proliferation and migrationinduces angiogenesis increases the cancer survivability. This evidence concerns the gene CDH1 and cancer.