Recently, bioinformatics-based prognostic models incorporating CCL26 have been developed for various cancers, including esophageal adenocarcinoma (Zhang et al., 2021), hepatocellular carcinoma (Hu et al., 2021) and OSCC (Zhao et al., 2021) have been constructed based on bioinformatics technology. This evidence concerns the gene CCL26 and esophageal adenocarcinoma.