Cell lines generated from iPSCs derived from CF patients with specific mutations, including F508del (Kondrateva et al., 2021), Asn1303Lys (Merkert et al., 2020), and S308X (Khor et al., 2022) also offer valuable resources for disease modeling and research on the pharmacological response to CFTR modulators (Cheng et al., 2023). Here, CFTR is linked to cystic fibrosis.