UCK2 and malignant colon neoplasm: UCK2 is an enzyme involved in pyrimidine nucleotide metabolism, and its increased activity has been linked to the occurrence and progression of several types of cancer, including breast, lung, and colon cancer (22, 24, 42), Due to the abnormal expression of UCK2 in these cancers, targeting UCK2 has been identified as a potential avenue for cancer treatment.