Cancer cells rely on SLC7A11 cystine input to maintain redox balance and cell survival, which can inhibit the occurrence of ferroptosis, and SLC7A11 downregulation and methylation can induce ferroptosis in endometrial cancer cells (12, 13), however, when the SLC7A11 gene is overexpressed and glucose deprivation occurs, disulfidptosis death is triggered. This evidence concerns the gene SLC7A11 and cancer.