CD8A and adenocarcinoma: In addition, mIF analysis showed that capecitabine + oxaliplatin + pembrolizumab (COP ) increased the densities of CD3+ and CD8+ T cells in G/GJ adenocarcinomas, and the degree of pathological reaction was related to the increase of aggregation of PanCK+ cells to CD3+ cells (52).The results above are similar to ours.