A lower degree of infiltration of CD163+ macrophages occurred in both tumor and total in the Io+Chemo versus Chemo (density: tumor, p=0.001, total, p=0.018; percentage: tumor, p=0.003, total, p=0.004; H-score: tumor, p=0.000, total, p=0.007). Here, CD163 is linked to neoplasm.