Cebpb is associated with neutrophil emergency granulopoiesis in murine myocardial infarction;[59]Ets2 modulates genes associated with development and apoptosis, and its expression is upregulated in blood polymorphonuclear leukocytes 24 h after stroke.[60] Expression of Egr1 is upregulated in the ischemic hemisphere with its deletion associated with larger infarction volume and worse neurological scores.[61] All of which indicating a functional switch of neutrophils into mature states. This evidence concerns the gene EGR1 and stroke disorder.