Such limitations necessarily preclude the assessment of naturally‐induced anti‐tumor T cell responses immediately following exposure to native tumor Ag, and thus it remains unclear from the clinical work to date whether the presence of incompletely differentiated T cells in TFLN results from suboptimal activation of T cells at this site or, alternatively, reflects the presence of T cells that had previously been exposed to tumor Ag within TILN before recirculating to TFLN within the same nodal basin. Here, RENBP is linked to neoplasm.