CD4 and neoplasm: However, even in the case of the progressive B16‐F1 model, we did not observe accumulation of CD4+ CD25+ FOXP3+ regulatory T cells (Tregs) in the lung‐draining LN over the course of tumor progression, and there was no difference in the frequency of these cells in the LN of tumor‐free versus tumor‐bearing mice (Figure S2).