Nkx2-1 and Foxa2 are co-expressed in normal AT2 cells, and they can also coordinately regulate lung cancer cell growth and identity in a context-specific manner (Orstad et al, 2022; Snyder et al, 2013; Camolotto et al, 2018; Little et al, 2021). The gene discussed is FOXA2; the disease is lung cancer.