In addition, when examining the tumour-infiltrating immune cells from these mice, we observed a significant increase in effector cytokine-secreting CD8+ T cells infiltrating the tumours of hexa-acylated LPS-supplemented mice (Fig. 4f), with a trend towards decreased immune activation in penta-acylated LPS-treated mice (Fig. 4f and Extended Data Fig. 8a). The gene discussed is CD8A; the disease is neoplasm.